In a piece to mark Childhood Cancer Awareness Month, Dr. Diana Martins Carvalho reflects on the vital support of families who generously donate tissue samples and funds that enable her research into childhood brain tumours. Diana is a post-doctoral training fellow in Professor Chris Jones' lab at the Institute for Cancer Research (ICR). M4K Pharma [...]
M4K Team publishes in the Journal of Medicinal Chemistry In the May and September 2020 issues of the Journal of Medicinal Chemistry, the M4K team and collaborators published two articles on M4K's open science approach and the chemistry progress to develop the inhibitors for ALK2 as a treatment for Diffuse Intrinsic Pontine Glioma (DIPG). 1. [...]
Listen to a recording of the Nov 2019 Monthly Scientific Meeting Listen to M4K Pharma's Scientific Update Meeting from November 6th, 2019 where our scientists and collaborators discuss the latest progress in our Medicines4Kids project for a deadly children's brain cancer called DIPG. Join us to hear first-hand how we are developing [...]
Our collaborator Dr Chris Jones and his fantastic team at The Institute of Cancer Research were profiled in The Observer for their work on DIPG with support from Abbie's Army. M4K Pharma is proud to be working with them to bring an affordable DIPG cure to patients.
SGC-Oxford team comes out in support of Brain Tumour Charity's Twilight Walk On September 29th 2019, the Brain Tumour Charity organized The Twilight Walk in Warwick, UK, to raise funds for research and patient support. M4K Pharma's DIPG project collaborators at the Structural Genomics Consortium (SGC)- University of Oxford took part in the event by [...]
Fostering open collaboration in drug development for paediatric brain tumours Wong et al. describe in Biochemical Society Transactions how open collaboration and an open drug discovery model, like the one used by M4K Pharma, can help overcome the challenges faced while researching therapies for rare paediatric brain tumours such as DIPG. Prognosis of childhood brain [...]
Listen to a recording of the August 2019 Monthly Scientific Meeting Listen to M4K Pharma's Scientific Update Meeting from August 7th, 2019 where our scientists and collaborators discussed the latest progress in our Medicines4Kids project for a deadly children's brain cancer called DIPG. Everyone is invited to hear first-hand how we are [...]
Study published on new drug class targeting ACVR1 mutation for DIPG Scientists at The Institute of Cancer Research, London, along with colleagues at the Structural Genomics Consortium in Oxford, have published their findings on a new drug class that can kill brain cancer cells with mutations in the ACVR1 gene and shrink tumours in mice. Mutated versions [...]
Listen to a recording of the April 24th 2019 Scientific Update Meeting Listen to our scientists and collaborators discuss the latest progress in M4K Pharma’s quest for a medicine for DIPG- a deadly children’s brain cancer. Everyone is invited to dial-in and join our live meetings. To find out when our next [...]
Recording of M4K Pharma’s Scientific Update Meeting – March 6th, 2019 Listen to our scientists and collaborators discuss the latest progress in M4K Pharma's quest for a medicine for DIPG- a deadly children's brain cancer. Everyone is invited to dial-in and join our live meetings. To find out when our next meeting will be, follow [...]
